3D nano fabrication for single molecule microscopy
The new focus-locking technique involves growing cell on glass coverslips with specially 3D-printed nanometre particles called ‘fiducials’, which act as markers to stabilise or ‘lock’ the microscope as it is recorded. Being able to control the 3D-architecture and positioning of the guide markers at the nanoscale means that microscopists have greater control of the imaging.
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