Authors and affiliations:João Carlos Silva a , b , c , ∗,Mário Dinis-Ribeiro b , c , Fernando Tavares d ,Diogo Libânio b , c a Gastroenterology Department, Unidade Local de Saúde Gaia e Espinho (ULSGE), Vila Nova de Gaia, Portugal b MEDCIDS, Faculty of Medicine, University of Porto, Portugal c Gastroenterology Department, RISE@CI-IPOP (Health…
Authors and Affiliations: Nuno Tiago Tavares1,2, Catarina Lourenço1,2,3, Vera Constâncio1,2, Fernanda Fernandes-Pontes1, Diana Fonseca1, Rui Silva-Santos4, Isaac Braga5, Joaquina Maurício6, Rui Henrique1,4,7, Michelle Liu8, Robert S. Weiss8, Aditya Bagrodia9, Carmen Jerónimo1,7, João Lobo1,4,7 1 – Cancer Biology and Epigenetics Group, Research Center of IPO Porto CI-IPOP/CI-IPOP@RISE-Associate Laboratory, Portuguese Oncology Institute of Porto IPO Porto, Porto…
This study, led by Sandra Casimiro and Luis Costa from the Oncology Translational Lab at GIMM CARE, part of the GIMM Foundation – Gulbenkian Institute for Molecular Medicine, demonstrates the potential efficacy of a novel therapeutic strategy for triple-negative breast cancer (TNBC) — an aggressive form of breast cancer for which treatment options are largely…
Researchers from the “Differentiation and Cancer” group at i3S, in collaboration with “Cancer Metastasis” and “Cell Division & Genomic Stability” groups and Carmen Jerónimo from IPO-Porto, elucidated the role of YTHDF3, a key m6A RNA “reader” protein, as a driver of gastric cancer (GC) progression and paclitaxel sensitivity. This new study, entitled “The RNA‑binding protein…
Authors and Affiliations: Tiago Brito-Rocha1#, Vera Constâncio1,2#, Pedro Leite-Silva3, Carina Carvalho-Maia1,4, José Pedro Sequeira1,2, Sofia Salta1, João Lobo1,4,9, Diana Inês Machado1, Sandra P. Nunes1, Rui Silva-Santos1,4, Rui Freitas1,5, Carlos Dias6, Cláudia Vieira7, Marta Soares7,8, Rui Henrique1,4,9, Carmen Jerónimo1,9 Os autores gostariam de agradecer a todos os doentes e indivíduos saudáveis (controlos) pela doação de amostras…
Authors and Affiliations: Mariana P. Coelho1,2, Pedro F. Farinha1, Leonor Côrte-Real3, Nádia Ribeiro3, Hugo Luiz1, Jacinta O. Pinho1, Rute Noiva4, Catarina Godinho-Santos1, Catarina Pinto Reis1,5, Isabel Correia3, Maria Manuela Gaspar1,5 1iMed ULisboa Research Institute for Medicines, Faculty of Pharmacy, Universidade de Lisboa, Lisboa, Portugal 2i3N CENIMAT, Department of Materials Science, NOVA School of Science and…
A prospective single-center demonstrated that the implementation of an endoscopic screening program in patients with head and neck neoplasia led to the detection of esophageal and/or gastric neoplasia in 21.7% of cases, most diagnosed at an early stage still amenable to endoscopic resection. An health economic analysis showed that the program implementation is cost-effective in…
A new peer-reviewed study from the Ipatimup independently evaluated Paige Prostate, an FDA artificial intelligence (AI) tool, in clinical practice. The findings, published in Pathology-Research and Practice, showed that AI-assisted pathological diagnoses were delivered 24 hours faster, aligned more closely with surgical specimens, improved identification of Grade Group 1 patients by 27%, and might help…
Authors and Affiliations:Patrícia Fontão1,2,3, Gustavo Ramos Teixeira4,5, Daniel Antunes Moreno1, Rui Ferreira Marques2,3, João Norberto Stavale6, Suzana Maria Fleury Malheiros6, Carlos Almeida Júnior7, Bruna Minniti Mançano1 and Rui Manuel Reis1,2,3 1Molecular Oncology Research Center, Barretos Cancer Hospital, Rua Antenor Duarte Vilela, 1331, Barretos, SP 14784-400, Brazil 2Life and Health Sciences Research Institute (ICVS), School of…
Authors and Affiliations: Raquel V Mendes 1, Joana M Ribeiro # 2, Helena Gouveia # 3, Cátia Rebelo de Almeida 1, Mireia Castillo-Martin 1 4, Maria José Brito 4, Rita Canas-Marques 4, Eva Batista 3, Celeste Alves 3, Berta Sousa 3, Pedro Gouveia 3, Miguel Godinho Ferreira 5, Maria João Cardoso 3 6, Fatima Cardoso…